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Missouri pro-lifers are campaigning to restore a middle-ground abortion policy permitting abortion until the 12th week of pregnancy, contrasting with the near-complete ban after Dobbs and the current permissive stance until fetal viability. A win in Missouri's upcoming ballot referendum would be significant for the pro-life movement, which has had limited success in recent abortion-related votes nationwide.

Missouri voters have the opportunity to weigh in on ballot measures directly affecting the dignity of the unborn in the upcoming November 3 midterm election. The election will also influence state leadership positions that may impact policies on mail-order chemical abortion and support for pregnancy help organizations in Missouri.