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Missouri voters will decide on Amendment 3, which seeks to reinstate the state's abortion ban with exceptions and restore regulations struck down by a judge, while opponents argue it overturns the 2024 reproductive rights amendment passed by voters. The campaign around Amendment 3 is tied to broader issues of voter power and political influence in Missouri, with related ballot measures addressing gerrymandering and legislative control over voter-approved initiatives.

Missouri's Amendment 3 would repeal the 2024 reproductive rights amendment and reinstate an abortion ban with exceptions for medical emergencies, certain fetal anomalies, and pregnancies from rape or incest within 12 weeks. Medical professionals and advocates in Missouri express concern that these exceptions could be difficult to implement, potentially limiting access to necessary abortion care despite the stated allowances.

Missouri-based nonprofit Her Health Her Future Missouri has contributed $2.9 million to the campaign supporting Amendment 3, which seeks to overturn the state's 2024 reproductive-rights amendment and reinstate an abortion ban with certain exceptions. The campaign has raised $5.3 million total, with most funding coming from Missouri donors, while the opposition campaign Stop the Ban has raised over $25.7 million, largely from out-of-state sources.